The Emperor's New Drugs: Exploding the Antidepressant Myth

The Emperor's New Drugs: Exploding the Antidepressant Myth

Irving Kirsch

Language: English

Pages: 240

ISBN: 0465022006

Format: PDF / Kindle (mobi) / ePub

Irving Kirsch has the world doubting the efficacy of antidepressants. Based on fifteen years of research, The Emperor's New Drugs makes an overwhelming case that what the medical community considered a cornerstone of psychiatric treatment is little more than a faulty consensus. But Kirsch does more than just criticize: He offers a path society can follow to stop popping pills and start proper treatment.

Going Amiss in Experimental Research (Boston Studies in the Philosophy of Science)

The Origin of Feces: What Excrement Tells Us About Evolution, Ecology, and a Sustainable Society

The Science of Shakespeare: A New Look at the Playwright's Universe

The Seven Daughters of Eve: The Science That Reveals Our Genetic Ancestry




















the lowest effective dose. So when increasing the dose of antidepressants, doctors are merely following the manufacturer’s advice, as reported in the Summary of Product Characteristics. If the dose response curve is flat and higher doses produce an ‘increased potential for undesirable effects’, why does the Summary of Product Characteristics advise doctors to triple the dose if patients do not respond well enough to a lower dose? The key to understanding this contradiction is our old and

Effect and the Power of Belief When our most recent - and most definitive - meta-analysis was published, the headlines in many newspapers blazoned that ‘antidepressants don’t work’.1 The Daily Telegraph headline phrased it more specifically, clarifying that antidepressants are ‘no better than dummy pills’,2 but even this headline was not entirely accurate. What our analyses actually showed was that antidepressants work statistically better than placebos, but that this statistical difference was

It is just not meaningful to try and estimate the effectiveness of medical treatment in general. Some medical treatments are extremely effective, whereas others have much smaller effects, and there are some medical conditions for which effective treatments have not yet been found. This is the basic problem with any attempt to evaluate the overall effectiveness of placebos, as Beecher and the Danish researchers had tried to do. There is not just one placebo effect. Instead, the placebo effect

Pathophysiological Mechanism or Marketing Myth?’, Trends Pharmacol Sci, no. 9 (2008) Craft, Lynette L. and M. Daniel Landers, ‘The Effects of Exercise on Clinical Depression and Depression Resulting from Mental Illness: A Metaregression Analysis’, Journal of Sport and Exercise Psychology 20 (1998): 339-57 CSIP, Choice and Access Programme, ‘Commissioning a Brighter Future: Improving Access to Psychological Therapies’, edited by Department of Health: Crown, 2007a ——, ‘Improving Access to

‘Effects of Optimism, Pessimism, and Trait Anxiety on Ambulatory Blood Pressure and Mood During Everyday Life’, Journal of Personality and Social Psychology 76 (1999): 104-13 Reeves, Roy R., Mark E. Ladner, Roy H. Hart and Randy S. Burke, ‘Nocebo Effects with Antidepressant Clinical Drug Trial Placebos’, General Hospital Psychiatry 29 (2007): 275-77 Reiss, S. and R. J. McNally, ‘The Expectancy Model of Fear’, in Theoretical Issues in Behavior Therapy, edited by S. Reiss and Richard R. Bootzin,

Download sample